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Ref-No: TA-5108


Manufacturing process for oxygenators of different volumes


With extracorporeal membrane oxygenation, the physician only has oxygenators in a few different sizes. A suitable volume would be particularly important for infants and small children in order to relieve the blood circulation.

The economic use of traditional manufacturing processes for different volume sizes of the manufactured oxygenators is severely limited due to the high tool costs and is linked to critical quantities of each volume size.

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FlexOxy is a novel manufacturing process for wound oxygenators. FlexOxy enables the production of oxygenators with different volumes with the same housing, the same core and the same fiber mats. The volume of the oxygenator and the size of the membrane surface are set by the position of the displaceable core in relation to the housing and by an adapted adhesive. The established production processes can be used with specific mastery of specific supplementary parameters such as core position and amount of joining substance.


  • Flexible adjustment of blood volume and membrane surface
  • Low cost
  • Use of one manufacturing process for different volumes

Scope of application

Commercialization includes manufacturing of oxygenators in different intermediate sizes despite keeping the existing production processes and without increasing production costs with size-independent approval.


A German and an international patent application have been filed. On behalf of RWTH Aachen, we offer interested companies the opportunity to license and further develop the technology.

PROvendis GmbH

Catherine Hartmann
+49.208 94105-46
Schloßstr. 11-15
45468 Mülheim an der Ruhr

Development status


Patent situation

  • DE pending
  • EP pending


Oxygenators, blood circulation, wound oxygenators, medical technology

Offer at Providers website

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