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Device for sample purification by paramagnetic beads

Ref-Nr: TA-P-1170


Kurzfassung

The invention discloses a device that enables bead purification and mixing of the sample without the need for moving the reaction plate from one deck position to the other and hence saving time and deck space.


Hintergrund

The use of paramagnetic beads (e.g. Ampure® or Dyna®) is a standard procedure for the purification of nucleic acids and proteins, especially in high throughput approaches using liquid-handling robots. Here we present the idea for a new device that enables bead purification and mixing of the sample without the need for moving the reaction plate from one deck position to the other, hence saving time and deck space.


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Lösung

After molecules of interest are captured, the paramagnetic beads can be concentrated at the side of the wells by turning on the electromagnets, and washing can then take place. To mix the samples, the four electromagnets surrounding each well can be turned on consecutively to stir the beads in the desired buffer.


Vorteile

  • High-throughput purification of nucleic acids or proteins using paramagnetic beads.
  • Mixing of the samples by consecutive activation of electromagnets surrounding the wells.
  • Enabling the construction of an All-In-One Cycler for the preparation of sequencing libraries.

Anwendungsbereiche

DKFZ is looking for a commercial partner to manufacture and distribute the device.


Deutsches Krebsforschungszentrum DKFZ

Dr. Frieder Kern
+49-6221-42-2952
f.kern@dkfz.de
www.dkfz.de
Adresse
Im Neuenheimer Feld 280
69120 Heidelberg



Entwicklungsstand

Prototyp


Stichworte

Devices

Angebot Anbieter-Website


Kontakt | Geschäftsstelle

TechnologieAllianz e. V.
Christiane Bach-Kaienburg
(Geschäftsstellenleiterin)

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D-45468 Mülheim an der Ruhr