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Minimal invasive right ventricular assist device


Post-operative right heart failure may develop in more than 40% of patients undergoing implantation of a left ventricular assist device (L-VAD) and cardiac transplantation. Early introduction of a right ventricular assist device (R-VAD) has been proven beneficial for this group of patients. However, most commercially available R-VADs are still associated with complications such as hemolysis, infection and need for anticoagulation. Thus they are only used for short-term application. Some devices provide long-term support, but due to the invasive implantation procedure they are usually offered as a last resort to critically ill patients after all other alternative treatments have been exhausted.

Consequently, there is still an unmet clinical need for  minimally invasive implantable R-VADs which can be used as bridge-to-recovery as well as destination therapy.

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The invention is based on a foldable conduit-free axial flow pump directly driven by an integrated miniature external-rotor motor. The foldable components include impeller blades, removable fixation structures and a stent. The system can be inserted via peripheral vessels in a collapsed form and is expanded in the pulmonary artery immediately after the pulmonary valve. In the case of bridge-to-recovery application, MIRVAD can easily be removed due to its robust but removable fixation clips. In contrast to available minimally invasive implantable R-VADs, the system generates higher torque at lower rotational speed and thereby minimizes wear.  As a result, MIRVAD is also suitable for long-term application.


  • Minimally invasive application
  • Suitable for bridge-to-recovery or destination therapy
  • Excellent hemocompatibility


A European patent application has been filed in July 2012. On behalf of RWTH Aachen University, PROvendis offers access to rights for commercial use or research collaboration with licensing option.

PROvendis GmbH

Martin van Ackeren
+49.208 94105-34
Schloßstr. 11-15
45468 Mülheim an der Ruhr




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Medizinisches Implantat, Kardiologisches Implantat, Axial Durchflusspumpe im Stent, minimal invasives rechtsseitiges Ventrikular Implantat

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