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Antisense Circular RNA as Therapeutic Compound for Treatment of Covid-19

Ref-Nr: TA-TM 1110


Kurzfassung

A new artificial circular RNA prevents SARS coronavirus 2 (SARS-CoV-2) from replicating in infected cells.


Hintergrund

The new SARS-CoV-2 has made the disease Covid-19 a pandemic with effects on all aspects of human life by spreading rapidly across the whole world. Despite the immense progress in the treatment of Covid-19 patients in recent months, there is an urgent need for effective and well-tolerated therapeutic options, alternatively to the current mRNA-based and other vaccination strategies.


Bilder & Videos


Lösung

The new circular RNA enables specific binding and inhibition of SARS coronavirus 2 and thus opens up new therapeutic approaches for the treatment of Covid-19. This mechanism of action can effectively prevent and treat infections with SARS-CoV-2.


Vorteile

  • The new circular RNA is much more stable than the corresponding linear RNA.
  • Circular RNA is designed to bind specifically to sequence-conserved regions of SARS-CoV-2 genome and subgenomic RNAs.
  • Circular RNA can easily be synthesized in preparative amounts and introduced into cells.

Anwendungsbereiche

  • Therapy of Covid-19
  • Early prevention of infections by SARS-CoV-2
  • Post-exposure prophylaxis (PEP) after contact with Covid-19 patients

Service

On behalf of its shareholder Justus-Liebig-Universität Giessen TransMIT GmbH is looking for cooperation partners or licensees for further development in Germany, Europe, US, and Asia.


TransMIT Gesellschaft für Technologietransfer mbH

Anouschka Ulherr
0641 946434
anouschka.ulherr@transmit.de

Adresse
Kerkrader Str. 3
35394 Gießen



Entwicklungsstand

Prototyp


Patentsituation

  • EP anhängig

Stichworte

Circular RNA, Covid-19, Therapy, Coronavirus, Compound, Post-exposure Prophylaxis, SARS-CoV-2

Angebot Anbieter-Website


Kontakt | Geschäftsstelle

TransferAllianz e. V.
Christiane Bach-Kaienburg
(Geschäftsführerin)

c/o TransMIT GmbH
Kerkrader Straße 3
D-35394 Gießen