Two-position controller with reduced control-value range

Liquid damper column with adjustable properties

Provided is a method to improve the rooting of cuttings, particularly for horticultural plants.

The inventors have developed two novel and complementary approaches for the treatment of MLD: The first approach is based on the natural products...

Correction of inter-system errors in hybrid AC/DC transmission systems

Transition-metal catalyst for the photocatalytic H2O decomposition

Researchers of the Niederrhein University have invented a method to produce electroluminescent textile surface by conventional printing methods.

Visual control of a swarm of cleaning robots

The novel powertrain integrated DC-DC converter for hybrid vehicles extends the familiar conventional inverter topology for operating the starter.

Optimized circuit for high frequency energy harvesting

Improved Low Frequency Sound Reproduction from Small Speaker Enclosures

Lossless excitation of thin optical waveguides by oblique incidence of semi-guided waves

This system, already realized as prototype, is capable of analyzing the oil content or other parameters in individual seeds from a bulk of seeds as...

New class of small molecules acting as SERPINA3 inhibitors, which are able to reduce PrPSc accumulation in prion-infected cell lines

The diagnosis of low-grade periprosthetic infections is difficult and time consuming. The invention provides a novel approach to differentiate highly...

Treatment of osteoporosis by inhibitors of sphingosine-1phosphatase (S1P)-lyase

The invention related to a process for the preparation of ligand- free gold nanoparticles (Au-NP).

Innovative Hybrid Nanoparticles Generating Singlet-Oxygen for Efficient Photodynamic Therapy (PDT):
These two novel types of nanomaterials and...

5-Ketofructose (5-KF) is the perfect sweetener. Thanks to the inventive method it is now possible to produce the substance efficiently and...

This technology was achieved by a cooperation between McGill University and DKFZ. Brain tumours, such as the highly aggressive glioblastoma multiforme...

[All in German] Temperaturstabilisierung ist bei hochauflösenden Mikroskopen sehr wichtig. Die von DKFZ entwickelte Technologie ermöglicht mit...

Despite its relatively high costs polycarbonates are in many cases the first choice if high quality synthetics are needed. Scientists from the Georg...

Metabolic engineered C. glutamicum with highly attractive glutarate titer, yield and productivity

Presented here is a filter unit that has one or multiple microwave resonators integrated into its filter material, whereby filter load can be...

Non-alcoholic fatty liver disease (NAFLD), comprising several liver diseases including NAFL and NASH, which is the most frequent liver disease...

Lung cancer is the leading cause of death among men and women in North America and attracts substantial pharmaceutical investment. However, in...

So far, the problem of sealing has been a major challenge when using rotary piston pumps. Piston rotors in conventional rotary piston pumps are based...

Chitosans are a family of functional biopolymers, typically produced by partial de-N-acetylation of chitin, one of the most abundant biopolymers in...

The Mastomys mouse model is the only existing natural laboratory model to investigate PV pathogenesis and tumor development in the skin, ear, eye and...

Colorectal cancer (CRC) is the third most common cancer worldwide accounting for 1.36 million new cases annually. Harmful overtreatment of patients...

This invention provides a novel therapeutic strategy to prevent and treat different types of cancer. The microRNAs can target cancer associated...

This technology utilizes a novel DNA vector platform for the safe and efficient generation of genetically engineered cells. This DNA vector system...

This invention is based on the assumption that large-angle, low-energy scatter (which is usually discarded) contains useful information about...

DKFZ developed an optical imaging detector for fluorescence and bioluminescence in small animal imaging, which is compatible for positron electron...

The site-directed modification of e.g. biomolecules is often time consuming and laborious. This invention provides a high yielding and highly specific...

DKFZ developed an optical imaging detector (25 mm x 100 mm photon sensor) for fluorescence and bioluminescence in small animal imaging, which is...

Optical techniques, such as bioluminescence and fluorescence, are emerging as powerful new modalities for molecular imaging in disease and therapy....

The technology specifies a novel device which allows to stabilize images of optical microscopes with high resolutions against externally induced...

Quadscanner for High Resolution Scanning Microscopes and Array Readers, a fast, adaptive optical scanning device; calibration with 4 galvanometers /...

“Ready to use kit” for simultaneous quantitative detection of up to 51 HPV genotypes. Kit contains internal quality and performance controls and...

Radiotherapy is a well-established method to treat certain tumor types in particular brain tumors. For fixation of the patient’s head a “mask” is...

The current invention provides a prophylactic HPV vaccine. Immunization against peptides from the HPV L2 protein gives a robust immune reaction that...

This invention provides a method for an easy, economical and reliable post-synthetic modification of nucleic acids.

The invention provides a long time culture model which can be used for the production of skin equivalents with a life span of at least 10 weeks.

Monoclonal Antibody against Neurofibromin as a diagnostic and prognostic Marker for Glioma Treatment. The proof of concept is established with Biopsy...

This hand exoskeleton allows the hand to regain its moving ability, e.g. in paralysis after a stroke. Thanks to its modular design, the exoskeleton...

Many light emitting entities routinely used, in cell biological settings show a dipole orientation. If the exact z position of the light emitting...

Currently, Multileaf Collimators (MLC) are established and state of the art in numerous devices for radiotherapy used for cancer treatment. However,...

The Wnt signaling pathway plays an important role in the regulation of cell proliferation and differentiation. Aberrant activation of the Wnt...

The invention is based on papillomavirus pseudovirions consisting of L1 and L2 proteins encapsulating Gaussia luciferase as a reporter system. Using...

We developed a new concept for on-patient visualization of anatomical data acquired with an arbitrary modality (typically CT or MRI). The method is...

• Novel concept for driving and controlling of multi leaf collimators based on the piezo electric effect.
• Leaf bedding and positioning is directly...

DKFZ inventors identified the Wnt secretion protein Evi/Gpr177 as new target, which is strikingly upregulated during glioma tumorigenesis in a...

Diagnosis and monitoring of IDH1/IDH2/IDH3 dependent diseases such as: Glioblastomas, astrocytoma, oligodendrogliomas, oligoastrocytoma, acute myeloid...

The invention relates to a peptide identical to human isocitrate dehydrogenase type 1 (IDH1) which can be used for diagnosis, vaccination and...

Virus-like particles (VLPs) of EBV, completely devoid of viral DNA, for the prevention of infectious mononucleosis (IM) and EBV-associated diseases...

Several limitations restrict conventional Fluorescence recovery after photobleaching (FRAP) application. Examples are:

1. Low temporal resolution,...

Synchronization and control of linear accelerator, multi-leaf collimator, gantry system, patient support system and x-ray beam generation system at...

Solving the problem of poor pharmacokinetics by using the Fc domain of IgG being conjugated to endostatin, a component of all monoclonal antibodies...

Labeled oligonucleotides are used in research and for diagnostic, therapeutic and industrial applications. Researchers from the DKFZ and the...

The here presented technology provides an apparatus for 4Pi STED which allows to generate a three-dimensional light intensity distribution comprising...

The linear servo MLC presented here provides various advantages over conventionally employed MLCs.

The invention provides a cell based high-throughput screening system for agents that influence DNA methylation by determining the methylation status...

Method for molecular distinction of tumor species using standard techniques like Illumina's HumanMethylation450 (450k) BeadChip.

The technology allows for direct and indirect detection of cancer tissue. It deals with a pharmaceutical compound consisting of three subdomains: (A)...

The invention describes a miRNA which interferes with glucocorticoid signalling and can therefore be used as a therapeutic target for e.g....

Scientists from Goethe University Frankfurt am Main developed a new method for micro-diamond synthesis. The method facilitates diamond ...

Spatio-temporal spectral equalization of spherically measured head-related transfer functions

For a fast and precise control of mechatronic systems usually non-linear PID controllers are used. The more nonlinearities a system contains, the more...

Novel chromatic phase plate designed for STED or RESOLFT fluorescence light microscopy.

The invention discloses an improved version of the chorionallantic membrane, for accurate quantification of metastatic cells in different organs of...

The present invention comprises the use of two serum/plasma markers for stage discrimination and prediction of survival as well as treatment response...

The invention discloses a device that enables bead purification and mixing of the sample without the need for moving the reaction plate from one deck...

The antibody of this invention is a mouse monoclonal antibody directed against SUMO176-86 recognizing SUMO1 of human, mouse, chicken and X. laevis. It...

The invention offers a plasma protein biomarker set that can be used as a diagnostic tool for diagnosis and stratification of colorectal cancer.

DKFZ researchers developed an actively switched beam splitter based on polarizing beam splitters in combination with a Pockels cell which can be used...

The mouse model faithfully mimics clinical conditions in HCC and allows evaluation of novel therapeutic strategies like immunotherapy or...

The technology enables the surgeon to place and navigate e.g. a laparoscope, within an organ in an extremely precise, safe, and reliable manner.

The invention offers an autoantibody set that can be used as a diagnostic tool for diagnosis and stratification of colorectal cancer patients.

The relative position of a microscope objective with regard to a sample is essential in imaging the sample using the microscope objective. The...

The proprietary technology includes a method, a computer program and an apparatus for estimating an optical property of a tissue from a photoacoustic...

Staining of tissue is a standard method in biological laboratories, but also in clinical environment for diagnostics such as immunohistochemistry...

Chronic myeloproliferative neoplasia (CMN) is associated with the JAK2-V617F mutation. Novel compounds and a new concept are provided for the...

The novel plasma sensor is based on the so-called active plasma resonance spectroscopy, whereby the sensor itself is flush-mounted in the wall of the...

Getting to know you chances of dying can be daunting but also can be rather useful and fascinating. The kit predicts all-cause mortality independent...

Here we present an innovative and fully bio-compatible delivery system (conjugate complex) that can, at the same time, transport a useful cargo and...

This multi-pass amplifier concept offers a previously unequalled output power in the kW range with a compact design and various scaling and...

This measuring instrument is able to determine the continuous wave power share of the total power of a pulsed laser reliably. This information is very...

The invention implements explicit MPC control laws on a massively parallel reconfigurable hardware (field programmable gate arrays or similar).

The "robust one-shot interferometry" (ROSI) developed at the University of Stuttgart has been optimized in several aspects and now offers a...

The technology comprises an immunogenic polypeptide comprising a multitude of papillomavirus (PV) L2 N-terminal peptides, corresponding to amino acids...

A pharmaceutically compatible iron chelator or a pro-drug thereof for use in treating and/or preventing cancer in a patient suspected or known to...

The invention offers a mixed protein and autoantibody set that can be used as a diagnostic tool for diagnosis, stratification and therapy monitoring...

The vaccine can be used in prophylactic and therapeutic approaches against infections with human papillomaviruses.

The technology provides a peptide array comprising at least 100 polypeptides expressed or expressible from a Chlamydia trachomatis genome or epitopes...

The new-patented actuator system for machine hammer peening with a highly dynamic short-stroke linear reluctance motor allows for the first time to...

With the present invention, the energy density of rechargeable batteries and the power density of supercapacitors can be improved.

Provided is a gene conferring resistance against Barley Yellow mosaic virus (BaYMV) and Barley mild mosaic virus (BaMMV). Plants can be selected based...

Carbon coated iron oxide and zinc ferrite nanoparticles

Early classification of aggressive prostate cancers