Darobactin is a promising lead structure for antibiotic development.
- Medicine and pharmaceutics
- Therapy and therapeutics
Darobactin is a promising lead structure for antibiotic development.
In search for active substances corresponding to ZIP-9 at the Justus-Liebig-Universität, tetrapeptides were identified by means of molecular...
At the Department of Veterinary Medicine at the Justus-Liebig-Universität Gießen, upon investigation of myoblasts, i.e. precursor cells of...
Hydrostatic sliding bearing with minimal leakage
Process for the electrochemical synthesis of thiophenols from phenols
Measuring device and measuring method for the temporally high-resolution representation of the actual move-ment of a muscle in relation to its...
The invention provides a baculovius based expression System for targeted down-regulation of any gene on the bacuiovirusgenome or the cellular ...
A new artificial circular RNA prevents SARS coronavirus 2 (SARS-CoV-2) from replicating in infected cells.
High-pressure and vacuum-proof sapphire glass windows in a metal flange for high temperatures
Long-term stable water electrolysis through electrode coating
TMPRSS2 and furin are both essential for proteolytic activation and spread of SARS-CoV-2 in human airway epithelial cells and provide promising drug...
The device allows direct insertion of the cannula into place in one go and enables the correction of mistakes without needing to start over
Polymer-particle light-cleavable carrier systems for photodynamic therapy (PDT)
A process for the spray freeze-drying of lipophilic compounds
Speed-adaptive isokinetic particle sampling
The technology relates to a process for a much cheaper and easier production of components with a precisely defined porosity. By applying the method...
The process according to the invention can be used primarily by manufacturers of cutting tools as well as by regrinding companies of rotationally...
The new diaplatin complexes show activity against human cancer cell lines, thus proving their applicability in cancer therapy.
At the Department of Veterinary Medicine at the Justus-Liebig-Universität Gießen, upon investigation of myoblasts, i.e. precursor cells of skeletal...
New drug target for treating open and closed wounds as well as chronic pain and itch
Fast and inexpensive on-site analysis for medically relevant substances such as glyphosate, toxins, pathogens, viruses or microRNA, which until now...
Manufacturing process for oxygenators of different volumes
The Clean Water Technology Lab CLEWATEC, a Helmholtz Innovation Lab located at Helmholtz-Zentrum Dresden-Rossendorf (HZDR), is an interface between...
The Helmholtz Innovation Lab BlitzLab is part of the Helmholtz-Zentrum Dresden-Rossendorf (HZDR). BlitzLab aims to develop and optimize methods of ...
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How cars learn to recognize their surroundings correctly
3D printer for large-volume components
New component for touchscreens and optoelectronic circuits
The Helmholtz Innovation Lab “FlexiSens” focuses on the development and application of a flexible and printable magnetic field sensors (Hall effect...
Here, an extremely simple and effective screening method for the identification of cell-compatible drugs against viruses such as SARS-CoV-2,...
High-Redshift BODIPY Dyes for 2-Photon Imaging
Scientists at the Karlsruhe Institute of Technology have developed environmentally stable and 2D printable inorganic thermoelectric materials on an...
Down-regulation of NCALD in spinal muscular atrophy and diseases with a disturbed calcium homeostasis
A new technology to fix and weld thin foils without laborious and expensive fixtures.
The invention addresses both the optimization of electrode forms for high frequency device operation as well as innovative solutions for their...
VEGF-multimer based apheresis to treat preeclampsia
The invention concerns the correct tracking of several objects, which can be seen in a video, and the simultaneous, correct identification of the...
The two-axis rotator ROTAX is an innovative component for the precise spatial alignment of material samples during measurements under extreme...
With the Tensormeter, all components of the electrical resistance of thin layers, such as silicon wafers, can be measured quickly and precisely with...
The torque sensor “ARGUS” uses magnetic fields to monitor mechanical loads in shafts and axes. With ARGUS eyes, the sensor measures a large number of...
Positron annihilation spectroscopy is a non-destructive method for the qualitative and quantitative analysis of material properties on the nanometer...
The invention concerns a novel, polymer-based drug depot system which is introduced into the human body, where it enables a continuous release of the...
Scientists at the University of Stuttgart have developed two new methods for spatially resolved single-shot FT spectroscopy, which can be used to...
The new test procedure simulates on a carrier material how the chemical substance or food acts on a certain metabolic process of the human body, e.g....
The new analytical method presented herein allows the qualitative and quantitative analysis of structurally isomeric compounds of a mixture by...
The technology according to the invention relates to the field of build-up welding, or the additive manufacturing of components made of metal
Nanoscopic zoomlenses, dynamic beam steering and holograms – thanks to an inventive combination of metamaterial on top of a phase change material, all...
Using an optical or electrical signal to change the chirality and therefore the optical activity in either the visible, infrared or THz spectrum for a...
Common-mode-free three-phase non-isolated on-board chargers
Intrinsically flame retardant polystyrene without halogens
Plasmonic nano-antenna made of Yttrium dihydride have optical properties, that can be changed reversely by adding hydrogen without being sensitive to...
Complex optics in small devices – by using several diffractive optical elements this is now possible. The optical elements are printed in one piece...
For passive collection of brake dust, the present brake dust collector uses a final separator to shed the dust containing boundary layer off the...
For efficient collection of brake or tire dust, this present brake dust collector uses an air feed to shed the dust containing boundary layer off the...
This technology (antenna array and algorithm) enables the precise identification of metallic objects and reduces electromagnetic reflection effects....
Laser amplifiers play an important role in industrial production processes. A constant high quality of the laser pulses is indispensable for an...
This robust trepanning optics with only one rotating element (grid mirror) offers great flexibility with regard to the realizable drill diameter/...
These broadband grating waveguide mirrors with a diffraction efficiency of 99.7 %, that are as well polarization and wavelength selective, can be...
The emitting spectral bandwidth of laser diodes for semiconductor diode lasers is optimally reduced to a very small range. Resonant waveguide grating...
Optogenetics as a new field of research in genetics analyses the effect of lasers on single cells.
Researchers at the University of Konstanz, Germany have developed a mineral plastic foam that, as a bio-inspired hybrid material, can solve many of...
The invention relates to a method for preventing fires in tank systems as well as several design examples for tank systems for methanol fuels with a...
This technology provides the fundamental for a native wound gel that is capable of comprehensive treatment of deep and large area wounds. Due to its...
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For the energy revolution, fuel cells play a key role for future energy systems. Especially solid oxide fuel cells (SOFC) are well-suited for...
Chimeric mutants of interferon alpha 2 and other interferon alpha subtypes with improved antiviral activity
A laser soldering process has been developed that outranges existing methods. The big advantage of disc lasers is that the laser active material can...
Thanks to a clever design of the laser disk itself, the depolarization caused by the two heat spreaders can be neutralized. This creates a very...
The development of a new kind of head spreader allows to control the contact surface between laser disc and head spreader. Through this invention, the...
A process for the production of fiber-reinforced metal foam, esp. aluminum foam
Instead of letting the seed beam cross the pump spot as often as 80 times, now a much smaller seed beam can be used for gridding the pump spot,...
The invention relates to an imaging optical system for dermatological diagnostics, which on the one hand visualizes diagnostically relevant ...
Radar-based plasma characterization
In people with bee venom allergies, a sting can cause a sometimes life-threatening anaphylactic reaction. This reaction is caused by IgE antibodies...
A particularly skin-friendly microemulsion is provided for hyposensitization against insect venom allergens, especially bee and wasp venom, but also...
Encrypted cooperative control for network systems
A coumarin-caged forskolin derivative for temporally controlled cellular cAMP production was synthesized. The water-soluble caged forskolin derivative...
Subject of the invention is a holder for microscopy slides, which allows freely adjusting and selecting the space between the slides, creating a...
The described technology concerns a tunnel field-effect transistor (TFET) with superior tunnelling currents.
This device converts multiphase media into homogeneous dispersions with fine bubbles, so they are able to undergo more efficient heat transfer in...
The invention addresses both a device and a method for determining the electrical resistance of an object.
We offer an affordable compact accelerator-based neutron source (CANS) that produces neutrons by the nuclear capture reaction between a low energy...
This mobile intensity tracker for solar module production withstands the high temperatures in a continuous furnace belt for a short time and can...
This method makes it possible to remotely check the software versions offered by a service provider without having to rely on dedicated interfaces or...
Environmentally friendly method of removing oil from water
New drug target for inflammatory and other diseases
New control method provides variable output voltages
Method for current measurement in half-bridge topologies
Method for inhibiting fibrosis with few side effects after glaucoma surgery
Therapy of Malaria and other infective diseases
By using suitable components, it is now possible to selectively switch the interaction of the laser pulses with the resonator elements on and off for...
Sealing the electric feeds of a sensor in direct fluid contact is a challenge, especially under extremely low temperatures. This connecting device...
To produce wood-based composites urea-formaldehyde resin is the most widely used binder. However, UF resins are susceptible to hydrolysis and ...
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