• New selective inhibitors for treatment of chronic inflammatory diseases, such as atherosclerosis, obesity and multiple sclerosis. 
• Inhibitors select...

• novel EphA2 kinase inhibitors that borrow the chemical scaffold of the drug Dasatinib
• higher selectivity compared to the existing non-designated...

• Macrocyclic peptides with drug-like properties
• Highly potent inhibitors of Aβ amyloid self-assembly
• Promising in vivo data from...

• in vitro, in vivo and ex vivo detection of calcium changes via NMR and MRI & Hyper-CEST
• in particular for diagnosing and/or monitoring treatment of...

• Capacitive sensors
• Wireless sensor networks
• Touch screens

Zweipunktregler mit reduziertem Stellgrößenband

An der Universität Stuttgart wurde eine neuartige Abdeckvorrichtung für Ladungsträger und Kleinladungsträger (KLT) entwickelt, die durch Verwendung...

Visuelle Steuerung eines Schwarms von Reinigungsrobotern

Diese neue und einzigartig potente Verbindung dämmt effektiv die signalbasierte Angriffs-Koordination unter pathogenen Keimen und die damit...

Quasi-verlustfreie Anregung dünner optischer Schichtwellenleiter durch schrägen Einfall halbgeführter Wellen

This system, already realized as prototype, is capable of analyzing the oil content or other parameters in individual seeds from a bulk of seeds as...

A biomimetic air-retaining Salvinia surface

Eine biomimetische Luft haltende Salvinia-Oberfläche

New class of small molecules acting as SERPINA3 inhibitors, which are able to reduce PrPSc accumulation in prion-infected cell lines.

Allergiediagnostik in sehr kleinen Blutproben

Das Verfahren macht den allergieauslösenden Prozess im Blut direkt sichtbar: Die Zellen der...

Treatment of osteoporosis by inhibitors of sphingosine-1phosphatase (S1P)-lyase

Gegenstand der Erfindung ist die Kombination eines Isomerisierungskatalysators mit einem Polymerisationskatalysator zur Herstellung eines Copolymers...

Der Unterboden beinhaltet ein großes Reservoir an Nährstoffen. Er dient als Wasserspeicher und Wachstumsraum der Pflanzenwurzeln. Zur Steigerung der...

Die Erfindung stellt ein neues Syntheseverfahren zur Verfügung, mit dem erstmals strukturperfektes unsubstituiertes Poly-(para-Phenylen) (PPP) mit...

Die Substanz 5-Ketofructose (5-KF) eignet sich hervorragend als Süßstoff und kann dank des erfindungsgemäßen Verfahrens nun auch effizient und...

Interconnected microchannels

Channels of subcellular size

Optimal Environment for cells

This technology was achieved by a cooperation between McGill University and DKFZ. Brain tumours, such as the highly aggressive glioblastoma multiforme...

Temperaturstabilisierung ist bei hochauflösenden Mikroskopen sehr wichtig. Die von DKFZ entwickelte Technologie ermöglicht mit Durchstrom von exakt...

Polycarbonate haben exzellente mechanische und optische Eigenschaften, sind jedoch aufgrund ihrer aufwendigen Produktion vergleichsweise teuer. ...

Mit der Erfindung des SOS-Systems ist es möglich, auch bei stärkeren Seegängen Ölteppiche von der Wasseroberfläche zu skimmen, d.h. aufzunehmen.

Strang-pressverfahren mit Gegendruck zur signifikanten Erhöhung der Druckfließgrenze von strang-gepressten Magnesiumlegierungen.

This invention enables efficient processing of pixels to increase the quality of a video sequence. The procedure is interesting for video sharing...

For the first time, this method offers active control of chaotic combustion instabilities that can occur undesirably in various combustion systems.

The invention enables the prediction of instability in a compressor, which allows an early warning in the event of a fault. The early warning system...

This process enables the generation of nanoparticles in spray flames which can be used, for example, as coating material, in electrical devices, for...

Multi-layer anchoring with at least one loop formed by double-sided carbon fibers.

Androgynous (high pressure) coupling device with an integrated ball valve for liquid and gaseous media

Improved method for the production of a beverage having an ethanol content of under 0.5 vol%.

The mobile, modular, multimodal biosignal acquisition architecture (M3BA) offers high-performance and high precision acquisition of multiple...

Method for the assessment of the endogenous antioxidative potential (EAP) of beer and other beverages

  Vorgestellt wird eine Filtereinheit in deren Filtermaterial ein oder mehrere Mikrowellenresonatoren integriert sind, die eine Überwachung des ...

Werkzeug zur Reduktion von  überdimensionierte Profilabschnitte bei Strangpressen.

Non-alcoholic fatty liver disease (NAFLD), comprising several liver diseases including NAFL and NASH, which is the most frequent liver disease...

Lung cancer is the leading cause of death among men and women in North America and attracts substantial pharmaceutical investment. However, in...

Ein an der Universität Stuttgart entwickelte Verfahren kombiniert das Fügen von Funktionselementen mit dem Thermoformen und ermöglicht dadurch die...

Bislang war die Dichtungsproblematik eine wesentliche Herausforderung beim Einsatz von Rotationskolbenpumpen. Kolbenläufer in herkömmlichen...

Chitosans are a family of functional biopolymers, typically produced by partial de-N-acetylation of chitin, one of the most abundant biopolymers in...

An der Ruhr-Universität Bochum wurde ein Verfahren zur Messung der hydraulischen Permeabilität von feinkörnigen und gemischtkörnigen Böden mit Hilfe...

Der Einsatz von Lichtbarrieren zum Verbergen von grünen Pflanzen vor herbivoren Insekten im Zusammenspiel mit anderen für die Umwelt schonenden...

The Mastomys mouse model is the only existing natural laboratory model to investigate PV pathogenesis and tumor development in the skin, ear, eye and...

Colorectal cancer (CRC) is the third most common cancer worldwide accounting for 1.36 million new cases annually. Harmful overtreatment of patients...

This invention provides a novel therapeutic strategy to prevent and treat different types of cancer. The microRNAs can target cancer associated...

This invention is based on the assumption that large-angle, low-energy scatter (which is usually discarded) contains useful information about...

DKFZ developed an optical imaging detector for fluorescence and bioluminescence in small animal imaging, which is compatible for positron electron...

DKFZ developed an optical imaging detector (25 mm x 100 mm photon sensor) for fluorescence and bioluminescence in small animal imaging, which is...

Optical techniques, such as bioluminescence and fluorescence, are emerging as powerful new modalities for molecular imaging in disease and therapy....

The technology specifies a novel device which allows to stabilize images of optical microscopes with high resolutions against externally induced...

Quadscanner for High Resolution Scanning Microscopes and Array Readers, a fast, adaptive optical scanning device; calibration with 4 galvanometers /...

Radiotherapy is a well-established method to treat certain tumor types in particular brain tumors. For fixation of the patient’s head a “mask” is...

Das innovative Sensorprinzip ist kompakt, robust, wartungsarm und flammenlos. Die Mitführung von entzündlichen Trägergasen ist nicht erforderlich,...

The current invention provides a prophylactic HPV vaccine. Immunization against peptides from the HPV L2 protein gives a robust immune reaction that...

This invention provides a method for an easy, economical and reliable post-synthetic modification of nucleic acids. 

Monoclonal Antibody against Neurofibromin as a diagnostic and prognostic Marker for Glioma Treatment. The proof of concept is established with Biopsy...

Der Indikatortest nach Oddy wird aktuell von zahlreichen Museen, Sammlungen und Archiven aufgrund seiner relativ einfachen Anwendung und geringen...

Dieses Hand-Exoskelett ermöglicht eine Wiederherstellung der Greiffähigkeit der Hand, z. B. bei Lähmung nach einem Schlaganfall. Durch einen modularen...

Many light emitting entities routinely used, in cell biological settings show a dipole orientation. If the exact z position of the light emitting...

Currently, Multileaf Collimators (MLC) are established and state of the art in numerous devices for radiotherapy used for cancer treatment. However,...

The Wnt signaling pathway plays an important role in the regulation of cell proliferation and differentiation. Aberrant activation of the Wnt...

We developed a new concept for on-patient visualization of anatomical data acquired with an arbitrary modality (typically CT or MRI). The method is...

• Novel concept for driving and controlling of multi leaf collimators based on the piezo electric effect
• Leaf bedding and positioning is directly...

DKFZ inventors identified the Wnt secretion protein Evi/Gpr177 as new target, which is strikingly upregulated during glioma tumorigenesis in a...

Diagnosis and monitoring of IDH1/IDH2/IDH3 dependent diseases such as: Glioblastomas, astrocytoma, oligodendrogliomas, oligoastrocytoma, acute myeloid...

The invention relates to a peptide identical to human isocitrate dehydrogenase type 1 (IDH1) which can be used for diagnosis, vaccination and...

Virus-like particles (VLPs) of EBV, completely devoid of viral DNA, for the prevention of infectious mononucleosis (IM) and EBV-associated diseases...

Synchronization and control of linear accelerator, multi-leaf collimator, gantry system, patient support system and x-ray beam generation system at...

Solving the problem of poor pharmacokinetics by using the Fc domain of IgG being conjugated to endostatin, a component of all monoclonal antibodies...

Labeled oligonucleotides are used in research and for diagnostic, therapeutic and industrial applications. Researchers from the DKFZ and the...

The here presented technology provides an apparatus for 4Pi STED which allows to generate a three-dimensional light intensity distribution comprising...

 The linear servo MLC presented here provides various advantages over conventionally employed MLCs.

The invention provides a cell based high-throughput screening system for agents that influence DNA methylation by determining the methylation status...

Method for molecular distinction of tumor species using standard techniques like Illumina's HumanMethylation450 (450k) BeadChip.

The invention describes a miRNA which interferes with glucocorticoid signalling and can therefore be used as a therapeutic target for e.g....

Scientists from Goethe University Frankfurt am Main developed a new method for micro-diamond synthesis. The method facilitates diamond formation at...

Räumlich-zeitlich-spektrale Entzerrung von sphärisch gemessenen kopfbezogenen Übertragungsfunktionen

Für eine schnelle und präzise Regelung von mechatronischen Systemen werden meist Regelungen auf Basis von nichtlinearen PID-Reglern verwendet. Je mehr...

Novel chromatic phase plate designed for STED or RESOLFT fluorescence light microscopy.

The invention discloses an improved version of the chorionallantic membrane, for accurate quantification of metastatic cells in different organs of...

The present invention comprises the use of two serum/plasma markers for stage discrimination and prediction of survival as well as treatment response...

The invention discloses a device that enables bead purification and mixing of the sample without the need for moving the reaction plate from one deck...

The antibody of this invention is a mouse monoclonal antibody directed against SUMO176-86 recognizing SUMO1 of human, mouse, chicken and X. laevis. It...

The invention offers a plasma protein biomarker set that can be used as a diagnostic tool for diagnosis and stratification of colorectal cancer.

DKFZ researchers developed an actively switched beam splitter based on polarizing beam splitters in combination with a Pockels cell which can be used...

The mouse model faithfully mimics clinical conditions in HCC and allows evaluation of novel therapeutic strategies like immunotherapy or...