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1209 Treffer

11. Diagnosis/monitoring of glioblastoma and acute myeloid leukemia by (D)-2-hydroxyglutarate test  
Diagnosis and monitoring of IDH1/IDH2/IDH3 dependent diseases such as: Glioblastomas, astrocytoma, oligodendrogliomas, oligoastrocytoma, acute myeloid leukaemia (AML), chondrosarcoma, intrahepatic...  
12. Peptide vaccine for treatment of IDH1 R132H mutant-positive cancers  
The invention relates to a peptide identical to human isocitrate dehydrogenase type 1 (IDH1) which can be used for diagnosis, vaccination and subsequent immunomonitoring of patients with various...  
13. Promising effective and safe Epstein-Barr virus (EBV) vaccine based on VLPs  
Virus-like particles (VLPs) of EBV, completely devoid of viral DNA, for the prevention of infectious mononucleosis (IM) and EBV-associated diseases like lymphomas often developed in patients with...  
14. Measurement of protein mobility and interactions in living cells by 3PEA  
Several limitations restrict conventional Fluorescence recovery after photobleaching (FRAP) application. Examples are: 1) Low temporal resolution, which prohibits measurements of faster processes 2)...  
15. Control of radiation therapy devices via PLC technology  
Synchronization and control of linear accelerator, multi-leaf collimator, gantry system, patient support system and x-ray beam generation system at the same time is difficult to establish,...  
16. Oligomerization improves endostatin as antiangiogenic and anticancer drug  
Solving the problem of poor pharmacokinetics by using the Fc domain of IgG being conjugated to endostatin, a component of all monoclonal antibodies approved for patients with a number of diseases...  
17. Multiple orthogonal labelling of oligonucleotides  
Labeled oligonucleotides are used in research and for diagnostic, therapeutic and industrial applications. Researchers from the DKFZ and the Heidelberg University developed a fast method for...  
18. 4Pi STED Fluorescence Light Microscope with high three-Dimensional Spatial Resolution  
The here presented technology provides an apparatus for 4Pi STED which allows to generate a three-dimensional light intensity distribution comprising a very steep light intensity gradient between the...  
19. Linear Servo Multileaf Collimator for radiotherapy  
 The linear servo MLC presented here provides various advantages over conventionally employed MLCs.  
20. Cell line for screening demethylating agents using an endogenous epigenetically silenced reporter  
The invention provides a cell based high-throughput screening system for agents that influence DNA methylation by determining the methylation status of an internal promoter.  

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