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1253 Treffer

61. Wnt pathway Inhibitor: New Substance Class for Promising Novel Anti-Tumor Agent  
The Wnt signaling pathway plays an important role in the regulation of cell proliferation and differentiation. Aberrant activation of the Wnt signaling pathway is known to promote uncontrolled cell...  
62. High-Throughput Method for Determining the Presence of Papillomavirus-Neutralizing Antibodies in a Sample  
The invention is based on papillomavirus pseudovirions consisting of L1 and L2 proteins encapsulating Gaussia luciferase as a reporter system. Using HeLaT K4 cells as target cells the screen can be...  
63. Mobile On-Patient Visualization Device of Medical Images  
We developed a new concept for on-patient visualization of anatomical data acquired with an arbitrary modality (typically CT or MRI). The method is based on a mobile device consisting of a flat...  
64. Piezo-controlled Positioning & Driving of Multi Leaf Collimators  
Novel concept for driving and controlling of multi leaf collimators based on the piezo electric effectLeaf bedding and positioning is directly combined with leaf driving  
65. Evi/Gpr177 as New Target in Wnt Signaling Pathway for Treating Various Cancer Types  
DKFZ inventors identified the Wnt secretion protein Evi/Gpr177 as new target, which is strikingly upregulated during glioma tumorigenesis in a stage-independent way and which correlated with poor...  
66. Diagnosis/Monitoring of Glioblastoma & Acute Myeloid Leukemia by (D)-2-Hydroxyglutarate Test  
Diagnosis and monitoring of IDH1/IDH2/IDH3 dependent diseases such as: Glioblastomas, astrocytoma, oligodendrogliomas, oligoastrocytoma, acute myeloid leukaemia (AML), chondrosarcoma, intrahepatic...  
67. Peptide Vaccine for Treatment of IDH1 R132H Mutant-Positive Cancers  
The invention relates to a peptide identical to human isocitrate dehydrogenase type 1 (IDH1) which can be used for diagnosis, vaccination and subsequent immunomonitoring of patients with various...  
68. Promising Efective & Safe Epstein-Barr Virus (EBV) Vaccine Based on VLPs  
Virus-like particles (VLPs) of EBV, completely devoid of viral DNA, for the prevention of infectious mononucleosis (IM) and EBV-associated diseases like lymphomas often developed in patients with...  
69. Measurement of Protein Mobility & Interactions in Living Cells by 3PEA  
Several limitations restrict conventional Fluorescence recovery after photobleaching (FRAP) application. Examples are: 1) Low temporal resolution, which prohibits measurements of faster processes 2)...  
70. Control of Radiation Therapy Devices via PLC Technology  
Synchronization and control of linear accelerator, multi-leaf collimator, gantry system, patient support system and x-ray beam generation system at the same time is difficult to establish,...  

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